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Literature summary for 2.7.11.13 extracted from
- Protein kinase C controls activation of the DNA integrity checkpoint (2014), Nucleic Acids Res., 42, 7084-7095.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + histone H2A | Saccharomyces cerevisiae | - |
ADP + phosphorylated histone H2A | - |
? |  |
| ATP + Rad53 protein | Saccharomyces cerevisiae | - |
ADP + phosphorylated Rad53 protein | - |
? | |
| ATP + Xras2 protein | Saccharomyces cerevisiae | - |
ADP + phosphorylated Xrs2 protein | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + histone H2A | - |
Saccharomyces cerevisiae | ADP + phosphorylated histone H2A | - |
? | |
| ATP + Rad53 protein | - |
Saccharomyces cerevisiae | ADP + phosphorylated Rad53 protein | - |
? | |
| ATP + Xras2 protein | - |
Saccharomyces cerevisiae | ADP + phosphorylated Xrs2 protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKC | - |
Saccharomyces cerevisiae |
| PKC1 | - |
Saccharomyces cerevisiae |
| PKCdelta | isoform | Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is required for activation of checkpoint kinases Mec1 and Tel1. Isoform PKCdelta is able to activate the DNA integrity checkpoint | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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