Any feedback?
Literature summary for 2.7.11.13 extracted from
- Protein kinase C bidirectionally modulates Ih and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel surface expression in hippocampal pyramidal neurons (2015), J. Physiol., 593, 2779-2792.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phorbol 12,13-diacetate | - |
Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + hyperpolarization-activated cyclic nucleotide-gated channel 1 protein | Rattus norvegicus | - |
ADP + phosphorylated hyperpolarization-activated cyclic nucleotide-gated channel 1 protein | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hippocampus | hippocampal pyramidal neurons | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + hyperpolarization-activated cyclic nucleotide-gated channel 1 protein | - |
Rattus norvegicus | ADP + phosphorylated hyperpolarization-activated cyclic nucleotide-gated channel 1 protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKC | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme activity modulates HCN1 channel phosphorylation and HCN1 surface expression | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
