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Literature summary for 2.7.11.13 extracted from

  • Van Wandelen, L.; Van Ameijde, J.; Ismail-Ali, A.; Van Ufford, H.; Vijftigschild, L.; Beekman, J.; Martin, N.; Ruijtenbeek, R.; Liskamp, R.
    Cell-penetrating bisubstrate-based protein kinase C inhibitors (2013), ACS Chem. Biol., 8, 1479-1487.
    View publication on PubMed
Search for more literature for 2.7.11.13

Inhibitors

Inhibitors Comment Organism Structure
staurosporine
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + CREB1 protein
-
 Homo sapiens ADP + phosphorylated CREB1 protein
-
 ?
ATP + KPCB protein
-
 Homo sapiens ADP + phosphorylated KPCB protein
-
 ?
ATP + myristoylated alanine-rich C-kinase (152-164)
-
 Homo sapiens ADP + phosphorylated myristoylated alanine-rich C-kinase (152-164)
-
 ?

Synonyms

Synonyms Comment Organism
PKCalpha isoform Homo sapiens
PKCtheta isoform Homo sapiens
PKCzeta isoform Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00023
-
 pH and temperature not specified in the publication Homo sapiens staurosporine