Any feedback?
Literature summary for 2.7.11.13 extracted from
- Specific protein kinase C isoforms are required for rod photoreceptor differentiation (2011), J. Neurosci., 31, 18606-18617.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| IGF-1 | - |
Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| eye | - |
Mus musculus | - |
| retina | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKC | - |
Mus musculus |
| PKC-beta1 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | PKC-beta1 and PKC-gamma are important for the development of retinal, as their absence completely inhibits rod differentiation | Mus musculus |
| physiological function | a significant decline of STAT3 tyrosine phosphorylation is observed by activation of PKC, while inhibition of PKC results in an increase of phosphorylated STAT3 along with a delayed cell cycle exit of progenitors with prolonged PCNA expression | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
