Activating Compound | Comment | Organism | Structure |
---|---|---|---|
anionic phospholipids | isozymes alpha, betaI, betaII, and gamma require anionic phospholipids for activity, isozymes delta, epsilon, eta, and theta do not | Cavia porcellus | |
diacylglycerol | isozymes alpha, betaI, betaII, and gamma require diacylglycerol for activity, isozymes delta, epsilon, eta, and theta do not | Cavia porcellus | |
additional information | the isozymes show varying activation requirements | Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | isozymes beta, gamma, delta, epsilon | Cavia porcellus | 5737 | - |
additional information | no isozyme delta in the nucleus | Cavia porcellus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | isozymes alpha, betaI, betaII, and gamma require Ca2+ for activity, isozymes delta, epsilon, eta, and theta do not | Cavia porcellus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Cavia porcellus | the enzyme is essential for transduction of signals in a wide range of cell types, including neurons | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
female and male, several isozymes | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
capillary | isozyme gamma | Cavia porcellus | - |
duodenum | isozymes gamma, and epsilon | Cavia porcellus | - |
endothelial cell | isozyme gamma | Cavia porcellus | - |
enteric nervous system | several isozymes | Cavia porcellus | - |
fibroblast | isozyme beta | Cavia porcellus | - |
glial cell | glial network | Cavia porcellus | - |
ileum | myenteric neurons, isozymes gamma, lambda, and epsilon | Cavia porcellus | - |
lymph vessel | isozyme gamma | Cavia porcellus | - |
additional information | tissue- and cell-type-specific expression of isozymes, overview, involved in regulation of organ, e.g. intestinal, function | Cavia porcellus | - |
myenteron | myenteric neuron, isozyme beta in submucosal ganglia of neurons, isozymes gamma, eta, and theta are present in intrinsic primary afferent neurons, but not in other myenteric neurons, low expression of isozyme alpha, isozyme epsilon | Cavia porcellus | - |
small intestine | myenteric neurons | Cavia porcellus | - |
smooth muscle | no isozyme beta, high expression of isozyme delta | Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is essential for transduction of signals in a wide range of cell types, including neurons | Cavia porcellus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKC | - |
Cavia porcellus |