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Literature summary for 2.7.11.11 extracted from

  • Islam, A.; Jones, H.; Hiroi, T.; Lam, J.; Zhang, J.; Moss, J.; Vaughan, M.; Levine, S.J.
    cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2 (2008), J. Biol. Chem., 283, 25364-25371.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
8-bromo-cAMP
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
H-89 specific inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cAMP-dependent PKA induces type I tumor necrosis factor receptor exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to A kinase-anchoring protein domains B and C of the guanine nucleotide exchange protein BIG2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cAMP-dependent PKA induces type I tumor necrosis factor receptor exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to A kinase-anchoring protein domains B and C of the guanine nucleotide exchange protein BIG2 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
PKA
-
 Homo sapiens
protein kinase A
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens
cAMP dependent Homo sapiens