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Literature summary for 2.7.11.11 extracted from

  • Bardales, J.R.; Hellman, U.; Villamarin, J.A.
    Identification of multiple isoforms of the cAMP-dependent protein kinase catalytic subunit in the bivalve mollusc Mytilus galloprovincialis (2008), FEBS J., 275, 4479-4489.
    View publication on PubMed
Search for more literature for 2.7.11.11

Inhibitors

Inhibitors Comment Organism Structure
PKI(5-24)
-
 Mytilus galloprovincialis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0125
-
 Kemptide C-subunit isoform C5, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis
0.0125
-
 Kemptide C-subunit isoform C6, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis
0.0147
-
 Kemptide C-subunit isoform C3, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis
0.0158
-
 Kemptide C-subunit isoform C1, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis
0.0186
-
 Kemptide C-subunit isoform C4, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis
0.0247
-
 Kemptide C-subunit isoform C2, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C Mytilus galloprovincialis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41300
-
 C-subunit isoform C4, estimated by SDS-PAGE Mytilus galloprovincialis
41900
-
 C-subunit isoform C1, estimated by SDS-PAGE Mytilus galloprovincialis
42800
-
 C-subunit isoform C3, estimated by SDS-PAGE Mytilus galloprovincialis
42800
-
 C-subunit isoform C5, estimated by SDS-PAGE Mytilus galloprovincialis
43400
-
 C-subunit isoform C2, estimated by SDS-PAGE Mytilus galloprovincialis
44500
-
 C-subunit isoform C6, estimated by SDS-PAGE Mytilus galloprovincialis

Organism

Organism UniProt Comment Textmining
Mytilus galloprovincialis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
DEAE-cellulose chromatography and Mono-S column chromatography Mytilus galloprovincialis

Source Tissue

Source Tissue Comment Organism Textmining
mantle contains PKA C-subunit isoforms C4, C5, and C6 Mytilus galloprovincialis
-
muscle posterior adductor muscle, contains PKA C-subunit isoforms C1, C2, and C3 Mytilus galloprovincialis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Kemptide
-
 Mytilus galloprovincialis ADP + Kemptide phosphate
-
 ?

Subunits

Subunits Comment Organism
tetramer
-
 Mytilus galloprovincialis

Synonyms

Synonyms Comment Organism
cAMP-dependent protein kinase catalytic subunit (C-subunit)
-
 Mytilus galloprovincialis
PKA
-
 Mytilus galloprovincialis

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mytilus galloprovincialis
cAMP dependent Mytilus galloprovincialis