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Literature summary for 2.7.10.2 extracted from

  • Reuven, N.; Adler, J.; Porat, Z.; Polonio-Vallon, T.; Hofmann, T.G.; Shaul, Y.
    The tyrosine kinase c-Abl promotes homeodomain-interacting protein kinase 2 (HIPK2) accumulation and activation in response to DNA damage (2015), J. Biol. Chem., 290, 16478-16488.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a [homeodomain-interacting protein kinase 2]-L-tyrosine Homo sapiens
-
 ADP + a [homeodomain-interacting protein kinase 2]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-
HEK-293T cell
-
 Homo sapiens
-
HEP-3B cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a [homeodomain-interacting protein kinase 2]-L-tyrosine
-
 Homo sapiens ADP + a [homeodomain-interacting protein kinase 2]-L-tyrosine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
c-ABL
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function tyrosine kinase c-Abl promotes homeodomain-interacting protein kinase 2 accumulation and activation in response to DNA damage Homo sapiens