Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | isoform Pyk2 is not a Ca2+-dependent kinase in T cells but instead, increased intracellular Ca2+ induces Pyk2 phosphorylation through production of reactive oxygen species. Ca2+-stimulated Pyk2 phosphorylation is dependent on Src-family kinase activity, even at the Pyk2 autophosphorylation site. Pyk2 phosphorylation in cytotoxic T-lymphocytes is not absolutely Ca2+-dependent but relies on the strength of T-cell receptor stimulation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q14289 | PYK2 | - |
Synonyms | Comment | Organism |
---|---|---|
proline-rich tyrosine kinase 2 | - |
Homo sapiens |
PTK2B | - |
Homo sapiens |
Pyk2 | - |
Homo sapiens |