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Literature summary for 2.7.10.2 extracted from

  • Issigonis, M.; Tulina, N.; de Cuevas, M.; Brawley, C.; Sandler, L.; Matunis, E.
    JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche (2009), Science, 326, 153-156.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + signal transducer and activator of transcription
-
 Drosophila melanogaster ADP + phospho-L-tyrosinyl-signal transducer and activator of transcription
-
 ?

Synonyms

Synonyms Comment Organism
JAK
-
 Drosophila melanogaster
Janus kinase
-
 Drosophila melanogaster

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Drosophila melanogaster

General Information

General Information Comment Organism
physiological function JAK-STAT signaling is required for germline stem cell and cyst progenitor cells maintenance in testis Drosophila melanogaster