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Literature summary for 2.7.10.2 extracted from
- JAK2 inhibitors: A reality? A hope? (2009), Clin. Lymphoma Myeloma, 9, S340-S345.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| V617F | the mutation is found in a significant portion of patients with myeloproliferative neoplasm, results in increased JAK2 tyrosine kinase activity, leading to clonal proliferation | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| INCB018424 | Jak2 inhibitor | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O60674 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| JAK2 | - |
Homo sapiens |
| Janus kinase 2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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