Any feedback?
Literature summary for 2.7.10.2 extracted from
- The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation (2008), J. Biol. Chem., 283, 11526-11534.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | Btk plays a critical role in osteoclast multinucleation by modulating the activity of the nuclear factor of activated T cells c1, NFATc1 | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [protein]-L-tyrosine | Mus musculus | - |
ADP + [protein]-L-tyrosine phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| bone marrow | - |
Mus musculus | - |
| osteoclast | osteoclast lineage cell, preosteoclast | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + [protein]-L-tyrosine | - |
Mus musculus | ADP + [protein]-L-tyrosine phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Bruton's tyrosine kinase | - |
Mus musculus |
| Btk | - |
Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
