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Literature summary for 2.7.10.2 extracted from
- Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes (2006), Immunol. Lett., 106, 34-41.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| tyrphostin 25 | p38 MAP kinase inhibitor SB203580 and protein tyrosine kinase inhibitor tyrphostin 25 combined can be used for inhibition of matrix metalloproteinase-9 expression, overview | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | p38 MAP kinase inhibitor SB203580 and protein tyrosine kinase inhibitor tyrphostin 25 combined can be used for inhibition of matrix metalloproteinase-9 expression, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| monocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | p38 MAP kinase inhibitor SB203580 and protein tyrosine kinase inhibitor tyrphostin 25 combined can be used for inhibition of matrix metalloproteinase-9 expression, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PTK | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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