Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alsterpaullone | at 0.01 mM: 66% inhibition of CHK, 81% inhibition of LCK, and 10% inhibition of CSK | Homo sapiens | |
indirubin-3'-monoxime | at 0.01 mM: 62% inhibition of CHK, 89% inhibition of LCK, but no inhibition of CSK | Homo sapiens | |
kenpaullone | at 0.01 mM: 35% inhibition of CHK, 85% inhibition of LCK, and 14% inhibition of CSK | Homo sapiens | |
additional information | no or poor inhibition of CHK1, LCK, and CSK by roscovitine | Homo sapiens | |
purvalanol | at 0.01 mM: 22% inhibition of CHK, 80% inhibition of LCK and CSK | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Chk1 | - |
Homo sapiens |
Csk | - |
Homo sapiens |
Lck | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
21 | - |
assay at room temperature | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |