Any feedback?
Literature summary for 2.7.10.2 extracted from
- Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro (1995), Mol. Biol. Cell, 6, 1333-1347.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + cdc2 | Drosophila melanogaster | the Cdc2-inhibitory kinase is required for preventing premature activation of the mitotic program. Maternally provided Dwee1 is sufficient for regulating Cdc2 during embryogenesis | ADP + phosphorylated cdc2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Drosophila melanogaster | P54350 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| central nervous system | expression of the enzyme remains high in the proliferating cells of the central nervous system well after cells in the rest of the embryo have ceased dividing | Drosophila melanogaster | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + cdc2 | - |
Drosophila melanogaster | ADP + phosphorylated cdc2 | - |
? | |
| ATP + cdc2 | the Cdc2-inhibitory kinase is required for preventing premature activation of the mitotic program. Maternally provided Dwee1 is sufficient for regulating Cdc2 during embryogenesis | Drosophila melanogaster | ADP + phosphorylated cdc2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Dwee1 | - |
Drosophila melanogaster |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
