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Literature summary for 2.7.10.2 extracted from

  • Lai, K.S.; Jin, Y.; Graham, D.K.; Witthuhn, B.A.; Ihle, J.N.; Liu, E.T.
    A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells (1995), J. Biol. Chem., 270, 25028-25036.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens JAK3 splice isoforms are functional in JAK3 signaling and may enrich the complexity of the intracellular response functional in IL-2 or cytokine signaling ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P52333
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-

Source Tissue

Source Tissue Comment Organism Textmining
blood cancer cell hematopoietic cancer cells Homo sapiens
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breast cancer cell
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 Homo sapiens
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breast cancer cell line
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 Homo sapiens
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carcinoma cell hematopoietic and epithelial cancer cells Homo sapiens
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epithelium epithelial cancer cells Homo sapiens
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hematopoietic cell
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 Homo sapiens
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hematopoietic cell hematopoietic and epithelial cancer cells Homo sapiens
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additional information three splice variants are isolated from different mRNA sources: breast, spleen, and activated monocytes. JAK3 splice isoforms are functional in JAK3 signaling and may enrich the complexity of the intracellular responses functional in IL-2 or cytokine signaling Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information JAK3 splice isoforms are functional in JAK3 signaling and may enrich the complexity of the intracellular response functional in IL-2 or cytokine signaling Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
Leukocyte janus kinase
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 Homo sapiens