Literature summary for 2.7.10.1 extracted from

Arisaka, M.; Nakamura, T.; Yamada, A.; Negishi, Y.; Aramaki, Y.
Involvement of protein kinase Cdelta in induction of apoptosis by cationic liposomes in macrophage-like RAW264.7 cells (2010), FEBS Lett., 584, 1016-1020.

Search for more literature for 2.7.10.1

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	the activation of PKCdelta is strongly related to the glycosaminoglycans, especially chondroitin sulfate on the plasma membrane	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
rottlerin	specific inhibitor of PKCdelta	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Mus musculus	5634	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
80000	-	full-length enzyme, SDS-PAGE	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + a [protein]-L-tyrosine	Mus musculus	-	ADP + a [protein]-L-tyrosine phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	PKCd eltais activated by phosphorylation of a tyrosine residue in the catalytic domain and a threonine residue in the regulatory domain	Mus musculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
RAW-264.7 cell	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + a [protein]-L-tyrosine	-	Mus musculus	ADP + a [protein]-L-tyrosine phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PKCdelta	-	Mus musculus
protein kinase Cdelta	-	Mus musculus

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Mus musculus

General Information

General Information	Comment	Organism
physiological function	PKCeltad is strongly associated with apoptosis induced by stearylamine-liposomes	Mus musculus

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Release 2023.1 (January 2023)