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Literature summary for 2.7.10.1 extracted from

  • Baldus, S.E.; Schaefer, K.L.; Engers, R.; Hartleb, D.; Stoecklein, N.H.; Gabbert, H.E.
    Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases (2010), Clin. Cancer Res., 16, 790-799.
    View publication on PubMed

Application

Application Comment Organism
medicine failure of EGFR antibody therapy in patients with wild type KRAS colorectal cancer may result from activating BRAF or PIK3CA mutations and false-negative sequencing results caused by intratumoral heterogeneity Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colorectal adenocarcinoma cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
Egfr
-
Homo sapiens
epidermal growth factor receptor
-
Homo sapiens