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Literature summary for 2.7.10.1 extracted from
- ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli (2006), Nat. Med., 12, 961-966.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| herceptin | - |
Homo sapiens | |
| herceptin | - |
Mus musculus | |
| herceptin | - |
Rattus norvegicus | |
| PKI-166 | - |
Homo sapiens |  |
| PKI-166 | - |
Mus musculus | |
| PKI-166 | 0.5 mM/kg body weight | Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 120000 | - |
SDS-PAGE | Mus musculus |
| 120000 | - |
SDS-PAGE | Homo sapiens |
| 120000 | - |
SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + a [protein]-L-tyrosine | Mus musculus | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? | |
| ATP + a [protein]-L-tyrosine | Homo sapiens | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? | |
| ATP + a [protein]-L-tyrosine | Rattus norvegicus | - |
ADP + a [protein]-L-tyrosine phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Schwann cell | - |
Mus musculus | - |
| Schwann cell | - |
Homo sapiens | - |
| Schwann cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + a [protein]-L-tyrosine | - |
Mus musculus | ADP + a [protein]-L-tyrosine phosphate | - |
? | |
| ATP + a [protein]-L-tyrosine | - |
Homo sapiens | ADP + a [protein]-L-tyrosine phosphate | - |
? | |
| ATP + a [protein]-L-tyrosine | - |
Rattus norvegicus | ADP + a [protein]-L-tyrosine phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| erbB2 receptor tyrosine kinase | - |
Mus musculus |
| erbB2 receptor tyrosine kinase | - |
Homo sapiens |
| erbB2 receptor tyrosine kinase | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Mus musculus | |
| ATP | - |
Homo sapiens | |
| ATP | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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