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Literature summary for 2.7.10.1 extracted from

  • Middlemas, D.S.; Meisenhelder, J.; Hunter, T.
    Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor (1994), J. Biol. Chem., 269, 5458-5466.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + protein tyrosine Rattus norvegicus phospholipase C-gamma 1 is directly phosphorylated by TrkB ADP + protein tyrosine phosphate
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q63604
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-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein major sites of autophosphorylation are in the region containing Tyr670, Tyr674, and Tyr675 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + protein tyrosine autophosphorylation Rattus norvegicus ADP + protein tyrosine phosphate
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?
ATP + protein tyrosine phospholipase C-gamma 1 is directly phosphorylated by TrkB Rattus norvegicus ADP + protein tyrosine phosphate
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?
ATP + protein tyrosine major sites of autophosphorylation are in the region containing Tyr670, Tyr674, and Tyr675 Rattus norvegicus ADP + protein tyrosine phosphate
-
?

Synonyms

Synonyms Comment Organism
BDNF/NT-3 growth factors receptor
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Rattus norvegicus
TrkB receptor
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Rattus norvegicus