Literature summary for 2.7.1.91 extracted from

Jung, I.D.; Lee, J.S.; Kim, Y.J.; Jeong, Y.I.; Lee, C.M.; Baumruker, T.; Billlich, A.; Banno, Y.; Lee, M.G.; Ahn, S.C.; Park, W.S.; Han, J.; Park, Y.M.
Sphingosine kinase inhibitor suppresses a Th1 polarization via the inhibition of immunostimulatory activity in murine bone marrow-derived dendritic cells (2007), Int. Immunol., 19, 411-426.

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Inhibitors

Inhibitors	Comment	Organism	Structure
sphingosine kinase inhibitor	can influence co-stimulatory molecules (CD40, CD80, CD86 and MHC class II) and cytokine production (IL-12 and IL-10) in murine bone marrow-derived dendritic cells. Sphingosine kinase inhibitor significantly inhibits co-stimulatory molecules in dendritic cells. Sphingosine kinase inhibitor suppresses IL-12 production by dendritic cells and IFN-gamma production by T cells	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bone marrow-derived dendritic cell	LPS stimulates Sphk activity	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
SPHK	-	Mus musculus

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Release 2023.1 (January 2023)