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Literature summary for 2.7.1.91 extracted from

  • Soldi, R.; Mandinova, A.; Venkataraman, K.; Hla, T.; Vadas, M.; Pitson, S.; Duarte, M.; Graziani, I.; Kolev, V.; Kacer, D.; Kirov, A.; Maciag, T.; Prudovsky, I.
    Sphingosine kinase 1 is a critical component of the copper-dependent FGF1 export pathway (2007), Exp. Cell Res., 313, 3308-3318.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.91

Cloned(Commentary)

Cloned (Comment) Organism
expressed in the adenovirus shuttle vector pAdlox Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-
membrane
-
 Mus musculus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Cu high affinity copper-binding protein Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q8CI15
-
-

Purification (Commentary)

Purification (Comment) Organism
G-Sepharose column chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
NIH-3T3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + sphingosine
-
 Mus musculus ADP + sphingosine 1-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
SK1
-
 Mus musculus
sphingosine kinase 1
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus