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Literature summary for 2.7.1.91 extracted from

  • Francy, J.M.; Nag, A.; Conroy, E.J.; Hengst, J.A.; Yun, J.K.
    Sphingosine kinase 1 expression is regulated by signalling through PI3K, AKT2, and mTOR in human coronary artery smooth muscle cells (2007), Biochim. Biophys. Acta, 1769, 253-265.
    View publication on PubMed
Search for more literature for 2.7.1.91

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293T cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole 0.001-0.008 mM, specific inhibition Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NYA1
-
-

Source Tissue

Source Tissue Comment Organism Textmining
coronary artery smooth muscle cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + sphingosine
-
 Homo sapiens ADP + sphingosine 1-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
sphingosine kinase 1
-
 Homo sapiens
SPHK1
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens