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Literature summary for 2.7.1.68 extracted from

  • Ugalde, J.M.; Rodriguez-Furlan, C.; Rycke, R.D.; Norambuena, L.; Friml, J.; Leon, G.; Tejos, R.
    Phosphatidylinositol 4-phosphate 5-kinases 1 and 2 are involved in the regulation of vacuole morphology during Arabidopsis thaliana pollen development (2016), Plant Sci., 250, 10-19.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate Arabidopsis thaliana
-
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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ecotype Col-0
-

Source Tissue

Source Tissue Comment Organism Textmining
plant epidermal cell of root tip Arabidopsis thaliana
-
pollen
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Arabidopsis thaliana
-
root tip
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
Arabidopsis thaliana ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
?

Synonyms

Synonyms Comment Organism
phosphatidylinositol 4-phosphate 5-kinase
-
Arabidopsis thaliana
PIP5K1 isoform Arabidopsis thaliana
PIP5K2 isoform Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana the enzyme transcript levels increase in response to auxin and indole 3-acetic acid up

General Information

General Information Comment Organism
malfunction the loss of function of isoforms PIP5K1 and PIP5K2 produces defects on vacuoles and exine wall in pollen grains Arabidopsis thaliana
physiological function phosphatidylinositol 4-phosphate 5-kinases 1 and 2 are involved in the regulation of vacuole morphology during Arabidopsis thaliana pollen development. Both isoforms are involved in protein trafficking to the vacuole in root tip epidermal cells Arabidopsis thaliana