Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-phosphoglycerate | allosteric activator. Regulation of the enzyme by a carboxylate molecule rather than a sugar phosphate may reflect a step in the evolution of glycolysis that predates the dominance of sugars in metabolism | Pyrobaculum aerophilum |
Cloned (Comment) | Organism |
---|---|
- |
Pyrobaculum aerophilum |
Crystallization (Comment) | Organism |
---|---|
hanging-drop vapor diffusion method at 18°C, crystal structure is determined to 2.2 A resolution | Pyrobaculum aerophilum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate | Pyrobaculum aerophilum | the enzyme catalyzes the final step of glycolysis | ADP + phosphoenolpyruvate | - |
? | |
ATP + pyruvate | Pyrobaculum aerophilum DSM 7523 | the enzyme catalyzes the final step of glycolysis | ADP + phosphoenolpyruvate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pyrobaculum aerophilum | Q8ZYE0 | - |
- |
Pyrobaculum aerophilum DSM 7523 | Q8ZYE0 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Pyrobaculum aerophilum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate | - |
Pyrobaculum aerophilum | ADP + phosphoenolpyruvate | - |
? | |
ATP + pyruvate | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum | ADP + phosphoenolpyruvate | - |
? | |
ATP + pyruvate | - |
Pyrobaculum aerophilum DSM 7523 | ADP + phosphoenolpyruvate | - |
? | |
ATP + pyruvate | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum DSM 7523 | ADP + phosphoenolpyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAE0819 | locus name | Pyrobaculum aerophilum |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme catalyzes the final step of glycolysis | Pyrobaculum aerophilum |