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Literature summary for 2.7.1.40 extracted from
- New roles for pyruvate kinase M2: working out the Warburg effect (2008), Trends Biochem. Sci., 33, 359-362.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | - |
Homo sapiens | ATP + pyruvate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PKM2 | - |
Homo sapiens |
| pyruvate kinase M2 | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | PKM2 enhances the use of glycolytic intermediates for macromolecular biosynthesis and tumor growth, PKM2 can clearly contribute to the development of aerobic glycolysis and the Warburg effect | Homo sapiens |
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Release 2023.1 (January 2023)
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