Literature summary for 2.7.1.40 extracted from

Wang, C.; Chiarelli, L.R.; Bianchi, P.; Abraham, D.J.; Galizzi, A.; Mattevi, A.; Zanella, A.; Valentini, G.
Human erythrocyte pyruvate kinase: characterization of the recombinant enzyme and a mutant form (R510Q) causing nonspherocytic hemolytic anemia (2001), Blood, 98, 3113-3120.

Search for more literature for 2.7.1.40

Application

Application	Comment	Organism
medicine	mutation R510Q causes nonspherocytic hemolytic anemia	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
R510Q	similar kinetics as wild type, but dramatically decreased stability toward heat, more susceptible to ATP inhibition	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
62000	-	4 * 62000, SDS-PAGE	Homo sapiens
240000	-	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P30613	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Subunits

Subunits	Comment	Organism
tetramer	4 * 62000, SDS-PAGE	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)