Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aciclovir | competitive inhibitor | Herpes simplex virus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.011 | - |
aciclovir monophosphate | - |
Herpes simplex virus | |
0.12 | - |
ganciclovir monophosphate | - |
Herpes simplex virus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Herpes simplex virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Herpes simplex virus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (E)-5-(2-bromovinyl)-2'-deoxyuridine | - |
Herpes simplex virus | ? | - |
? | |
ATP + aciclovir monophosphate | - |
Herpes simplex virus | ? | - |
? | |
ATP + ganciclovir monophosphate | - |
Herpes simplex virus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HSV-1 TK | - |
Herpes simplex virus |
type 1 thymidine kinase | - |
Herpes simplex virus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0253 | - |
(E)-5-(2-bromovinyl)-2'-deoxyuridine | determined by capillary electrophoresis method | Herpes simplex virus | |
0.0272 | - |
ganciclovir monophosphate | determined by capillary electrophoresis method | Herpes simplex virus | |
0.238 | - |
aciclovir monophosphate | determined by capillary electrophoresis method | Herpes simplex virus |