Any feedback?
Literature summary for 2.7.1.21 extracted from
- Characterization of thymidine kinase and phosphorylation of deoxyribonucleosides in Chlamydomonas reinhardti (1979), Mol. Gen. Genet., 175, 399-409.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-bromodeoxyuridine | - |
Chlamydomonas reinhardtii |  |
| 5-fluorodeoxyuridine | - |
Chlamydomonas reinhardtii | |
| deoxyuridine | - |
Chlamydomonas reinhardtii | |
| dTDP | - |
Chlamydomonas reinhardtii | |
| dTTP | - |
Chlamydomonas reinhardtii | |
| dUDP | - |
Chlamydomonas reinhardtii | |
| dUTP | - |
Chlamydomonas reinhardtii | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00015 | - |
thymidine | pH 8.5, 30°C | Chlamydomonas reinhardtii | |
| 0.015 | - |
ATP | pH 8.5, 30°C | Chlamydomonas reinhardtii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 80000 | 85000 | gel filtration | Chlamydomonas reinhardtii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Chlamydomonas reinhardtii | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| ATP + thymidine = ADP + dTMP | mechanism | Chlamydomonas reinhardtii |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, 20 h | Chlamydomonas reinhardtii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + thymidine | ATP can be substituted by dCTP | Chlamydomonas reinhardtii | ADP + dTMP | - |
? | |
| ATP + thymidine | ATP can be substituted by dATP | Chlamydomonas reinhardtii | ADP + dTMP | - |
? | |
| ATP + thymidine | ATP can be substituted by CTP | Chlamydomonas reinhardtii | ADP + dTMP | - |
? | |
| additional information | overview: phosphoryl donors | Chlamydomonas reinhardtii | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Chlamydomonas reinhardtii |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
best value for stability | Chlamydomonas reinhardtii |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00013 | - |
5-bromodeoxyuridine | pH 8.5, 30°C | Chlamydomonas reinhardtii | |
| 0.00072 | - |
5-fluorodeoxyuridine | pH 8.5, 30°C | Chlamydomonas reinhardtii | |
| 0.00146 | - |
deoxyuridine | pH 8.5, 30°C | Chlamydomonas reinhardtii | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
