Literature summary for 2.7.1.153 extracted from

Zhang, X.; Deng, H.X.; Zhao, X.; Su, D.; Chen, X.C.; Chen, L.J.; Wei, Y.Q.; Zhong, Q.; Li, Z.Y.; He, X.; Yi, T.
RNA interference-mediated silencing of the phosphatidylinositol 3-kinase catalytic subunit attenuates growth of human ovarian cancer cells in vitroand in vivo (2009), Oncology, 77, 22-32.

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Protein Variants

Protein Variants	Comment	Organism
additional information	suppression of the PI3K catalytic subunit p110alpha inhibits the growth of ovarian cancer cells in vitro and in vivo	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
ovary cancer cell	-	Homo sapiens	-
SKOV-3 cell	an epithelial ovarian cancer cell line SKOV3 with constitutively active PI3K	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PI3K	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	suppression of the PI3K catalytic subunit p110alpha inhibits the growth of ovarian cancer cells in vitro and in vivo, inhibiting decreased cell viability and induced cell apoptosis	Homo sapiens

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Release 2023.1 (January 2023)