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Literature summary for 2.7.1.137 extracted from
- Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease (2007), J. Pharmacol. Exp. Ther., 321, 1-8.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | inhibitors of PI3K/Akt may prove to be useful novel therapies in the treatment of asthma and chronic obstructive pulmonary disease | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | PI3K family plays a prominent role in various inflammatory cells by controlling cell growth, differentiation, survival, proliferation, migration, and mediator production (such as cytokines) through its downstream components | Homo sapiens | ? | - |
? |  |
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