Inhibitors | Comment | Organism | Structure |
---|---|---|---|
LY301497 | - |
Bos taurus | |
LY301497 | - |
Gallus gallus | |
Wortmannin | - |
Bos taurus | |
Wortmannin | - |
Gallus gallus | |
Wortmannin | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Gallus gallus | PI 3-kinase activity is a necessary step in the regulation of bone resorption | ? | - |
? | |
additional information | Bos taurus | PI 3-kinase activity is a necessary step in the regulation of bone resorption | ? | - |
? | |
additional information | Rattus norvegicus | PI 3-kinase activity appears to be an important component of ovariectomy-stimulated bone loss in rats | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Gallus gallus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
osteoclast | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidylinositol | - |
Gallus gallus | ADP + phosphatidylinositol 3-phosphate | - |
? | |
ATP + 1-phosphatidylinositol | - |
Rattus norvegicus | ADP + phosphatidylinositol 3-phosphate | - |
? | |
ATP + 1-phosphatidylinositol | - |
Bos taurus | ADP + phosphatidylinositol 3-phosphate | - |
? | |
additional information | PI 3-kinase activity is a necessary step in the regulation of bone resorption | Gallus gallus | ? | - |
? | |
additional information | PI 3-kinase activity is a necessary step in the regulation of bone resorption | Bos taurus | ? | - |
? | |
additional information | PI 3-kinase activity appears to be an important component of ovariectomy-stimulated bone loss in rats | Rattus norvegicus | ? | - |
? |