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Literature summary for 2.7.1.137 extracted from

  • Morgan, S.J.; Smith, A.D.; Parker, P.J.
    Purification and characterization of bovine brain type I phosphatidylinositol kinase (1990), Eur. J. Biochem., 191, 761-767.
    View publication on PubMed
Search for more literature for 2.7.1.137

Inhibitors

Inhibitors Comment Organism Structure
Mg2+ inhibition above 2.5 mM, activation below Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.034
-
 phosphatidylinositol sonicated Bos taurus
0.067
-
 ATP
-
 Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ activation Bos taurus
Mg2+ Km: 6.9 mM Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
 x * 85000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
type I phosphatidylinositol kinase Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0017
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidylinositol
-
 Bos taurus ADP + phosphatidylinositol 3-phosphate
-
 ?
ATP + phosphatidylinositol 4,5-bisphosphate weak activity Bos taurus ADP + phosphatidylinositol 3,4,5-trisphosphate
-
 ?
ATP + phosphatidylinositol 4-phosphate weak activity Bos taurus ADP + phosphatidylinositol 3,4-bisphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 85000, SDS-PAGE Bos taurus