Literature summary for 2.7.1.1 extracted from

Ahn, K.J.; Kim, J.; Yun, M.; Park, J.H.; Lee, J.D.
Enzymatic properties of the N- and C-terminal halves of human hexokinase II (2009), BMB Rep., 42, 350-355.

Search for more literature for 2.7.1.1

Inhibitors

Inhibitors	Comment	Organism	Structure
D-glucose 6-phosphate	feedback-inhibition in response to the physiologic concentration of D-glucose 6-phosphate	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.37	-	D-glucose	wild type hexokinase II	Homo sapiens
0.81	-	ATP	wild type hexokinase II	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
SNU-449 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + D-glucose	hexokinase II displays high affinity for D-glucose	Homo sapiens	ADP + D-glucose 6-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
hexokinase II	isozyme	Homo sapiens
HKII	isozyme	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.24	-	D-glucose 6-phosphate	wild type hexokinase II	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)