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Literature summary for 2.6.1.2 extracted from
- Inhibition study of alanine aminotransferase enzyme using sequential online capillary electrophoresis analysis (2014), Anal. Biochem., 467, 28-30.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | sequential online capillary electrophoresis assay to study enzyme inhibitors. Evolution of the inhibition reaction can be achieved by automatically and simultaneously monitoring the substrate consumption and product formation as a function of reaction time | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| licorice | traditional Chinese medicine, competitive, reversible | Homo sapiens | |
| Qingkailing | traditional Chinese medicine, noncompetitive, reversible | Homo sapiens | |
| succinic acid | competitive, reversible | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-alanine + 2-oxoglutarate | - |
Homo sapiens | pyruvate + L-glutamate | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.15 | - |
succinic acid | pH 7.5, temperature not specified in the publication | Homo sapiens | |
| 1.16 | - |
licorice | pH 7.5, temperature not specified in the publication | Homo sapiens | |
| 1.61 | - |
Qingkailing | pH 7.5, temperature not specified in the publication | Homo sapiens |
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Release 2023.1 (January 2023)
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