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Literature summary for 2.6.1.19 extracted from
- Probing the steric requirements of the gamma-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin (2013), Bioorg. Med. Chem., 21, 903-911.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| vigabatrin | - |
Sus scrofa |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.2 | - |
4-aminobutanoate | pH 8.6, temperature not specified in the publication | Sus scrofa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-aminobutanoate + 2-oxoglutarate | - |
Sus scrofa | 4-oxobutanoate + L-glutamate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GABA-AT | - |
Sus scrofa |
| gamma-aminobutyric acid aminotransferase | - |
Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.6 | - |
assay at | Sus scrofa |
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Release 2023.1 (January 2023)
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