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Literature summary for 2.6.1.19 extracted from

  • Tunnicliff, G.; Ngo, T.T.; Rojo-Ortega, J.M.; Barbeau, A.
    The inhibition by substrate analogues of gamma-aminobutyrate aminotransferase from mitochondria of different subcellular fractions of rat brain (1977), Can. J. Biochem., 55, 479-484.
    View publication on PubMed
Search for more literature for 2.6.1.19

Inhibitors

Inhibitors Comment Organism Structure
2,4-diaminobutanoate kinetics Rattus norvegicus
Aminooxyacetate kinetics Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.5
-
 4-aminobutanoate mitochondrial enzyme Rattus norvegicus
6.5
-
 4-aminobutanoate pH 8.0 Rattus norvegicus
53
-
 4-aminobutanoate synaptosomal enzyme, pH 8.0 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Rattus norvegicus 5739
-
synaptosome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-aminobutanoate + 2-oxoglutarate
-
 Rattus norvegicus 4-oxobutanoate + L-glutamate
-
 r
beta-alanine + 2-oxoglutarate
-
 Rattus norvegicus malonic semialdehyde + L-glutamate
-
 r

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.008
-
 2,4-diaminobutanoate synaptosomal enzyme, pH 8.0 Rattus norvegicus
0.013
-
 2,4-diaminobutanoate cytoplasmic enzyme, pH 8.0 Rattus norvegicus