Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | of seven major rat isoenzymes | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
additional information | microsomal enzyme is clearly distinct from cytosolic | Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RX + glutathione | Rattus norvegicus | may be involved in preventing lipid peroxidation | HX + R-S-glutathione | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.00242 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + 1,2-dichloro-4-nitrobenzene | - |
Rattus norvegicus | ? | - |
? | |
glutathione + 1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | S-2,4-dinitrophenylglutathione + HCl | - |
? | |
glutathione + cumene hydroperoxide | - |
Rattus norvegicus | ? | - |
? | |
additional information | - |
Rattus norvegicus | ? | - |
? | |
RX + glutathione | RX: R: aliphatic, aromatic or heterocyclic, X: sulfate, nitrite or halide, enzyme also catalyzes: the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrite, certain isomerization reactions and disulfide interchange | Rattus norvegicus | HX + R-S-glutathione | - |
? | |
RX + glutathione | may be involved in preventing lipid peroxidation | Rattus norvegicus | HX + R-S-glutathione | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8 | - |
Rattus norvegicus |