Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.15 extracted from

  • Gibreel, A.; Skold, O.
    Sulfonamide resistance in clinical isolates of Campylobacter jejuni: mutational changes in the chromosomal dihydropteroate synthase (1999), Antimicrob. Agents Chemother., 43, 2156-2160.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
cloning of a sulfonamide resistant strain Campylobacter jejuni

Inhibitors

Inhibitors Comment Organism Structure
sulfathiazole competitive to 4-aminobenzoate Campylobacter jejuni

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00085
-
4-Aminobenzoate sulfonamide resistant enzyme Campylobacter jejuni

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate
-
Campylobacter jejuni diphosphate + 7,8-dihydropteroate
-
?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.5
-
sulfathiazole resistant enzyme Campylobacter jejuni