Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.4 extracted from

  • Fujimoto, K.; Matsumura, Y.; Tani, Y.; Ozono, S.; Hirao, Y.; Okajima, E.
    Tissue levels of pyrimidine nucleoside phosphorylase activity in human and rodent bladder cancer and normal bladder tissue (2007), Int. J. Urol., 14, 754-759.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens P19971
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bladder higher PyNpase levels in normal tissue adjacent to tumor, AN, than in normal tissue, N Homo sapiens
-
bladder transitional cell carcinoma cell higher PyNpase levels in tumor tissue than in normal tissue or tissue adjacent to the tumor, PyNpase levels independent of age, gender, history of recurrence, multiplicity, tumor size, tumor shape, pathological stage (Ta, T1-4), PyNpase levels differ between histological stages being highest in G3, and between papillary versus non-papillary growth pattern, higher PyPnase levels in high-risk group (G3 or Tis or T2) than in low-risk group (primary, single, G1 and Ta) Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
thymidine + phosphate
-
Homo sapiens thymine + alpha-D-deoxyribose 1-phosphate
-
r

Synonyms

Synonyms Comment Organism
pynpase
-
Homo sapiens
pyrimidine nucleoside phosphorylase
-
Homo sapiens
thymidine phosphorylase
-
Homo sapiens