Application | Comment | Organism |
---|---|---|
medicine | the enzyme constitutes a target for antitrichomonial chemotherapy | Trichomonas vaginalis |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trichomonas vaginalis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Formycin A | - |
Trichomonas vaginalis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
6.1 | - |
adenosine | - |
Trichomonas vaginalis | |
12.3 | - |
adenine | - |
Trichomonas vaginalis | |
31.5 | - |
Inosine | - |
Trichomonas vaginalis | |
35.9 | - |
guanine | - |
Trichomonas vaginalis | |
45.6 | - |
hypoxanthine | - |
Trichomonas vaginalis | |
59.7 | - |
guanosine | - |
Trichomonas vaginalis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trichomonas vaginalis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Trichomonas vaginalis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine + phosphate | in the reverse reaction the catalytic activity with adenine is higher than that with either hypoxanthine or guanine | Trichomonas vaginalis | adenine + alpha-D-ribose 1-phosphate | - |
r | |
guanosine + phosphate | - |
Trichomonas vaginalis | guanine + alpha-D-ribose 1-phosphate | - |
r | |
inosine + phosphate | - |
Trichomonas vaginalis | hypoxanthine + alpha-D-ribose 1-phosphate | - |
r |