Cloned (Comment) | Organism |
---|---|
His tagged truncated protein expressed in High Five cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D519H | inactivated lectin domain | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ion exchange chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-alpha-D-galactosamine + (glycosylated GTTPSPVPTTSTTSAP) | natural-type (alpha-GalNAc-O-Thr) and unnatural-type (beta-GalNAc-O-Thr, alpha-Fuc-O-Thr and beta-GlcNAc-O-Thr) glycosylated | Homo sapiens | UDP + ? | - |
? | |
UDP-N-acetyl-alpha-D-galactosamine + GTTPSPVPTTSTTSAP | - |
Homo sapiens | UDP + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 | - |
Homo sapiens |
uridine diphosphate-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the lectin domain strictly recognizes GalNAc on the substrate and this specificity controls the glycosylation pathway | Homo sapiens |