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Literature summary for 2.4.1.41 extracted from

  • Stwora-Wojczyk, M.M.; Dzierszinski, F.; Roos, D.S.; Spitalnik, S.L.; Wojczyk, B.S.
    Functional characterization of a novel Toxoplasma gondii glycosyltransferase: UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3 (2004), Arch. Biochem. Biophys., 426, 231-240.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
stable transfected into Drosophila melanogaster S2 cells Toxoplasma gondii

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0141
-
UDP-N-acetyl-D-galactosamine pH 7.0, 37°C Rattus norvegicus
0.0209
-
GTTPSPVPTTS-(O-GalNAc)T-SAP pH 7.0, 37°C Rattus norvegicus
0.0259
-
GTTPSPVPTTSTTSAP pH 7.0, 37°C Mus musculus
0.044
-
UDP-N-acetyl-D-galactosamine pH 7.0, 37°C Toxoplasma gondii
0.0721
-
GTTPSPVPTTS-(O-GalNAc)T-SAP pH 7.0, 37°C Toxoplasma gondii
0.0788
-
UDP-N-acetyl-D-galactosamine pH 7.0, 37°C Mus musculus
0.1058
-
PTTDS-(O-GalNAc)T-TPAPTTK pH 7.0, 37°C Rattus norvegicus
0.182
-
PTTDS-(O-GalNAc)T-TPAPTTK pH 7.0, 37°C Toxoplasma gondii
0.198
-
PTTDS-(O-GalNAc)T-TPAPTTK pH 7.0, 37°C Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Toxoplasma gondii Q6YBY0
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Toxoplasma gondii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + GTTPSPVPTTS-(O-GalNAc)T-SAP
-
Rattus norvegicus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + GTTPSPVPTTS-(O-GalNAc)T-SAP
-
Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + GTTPSPVPTTS-(O-GalNAc)T-SAP 23% of the activity with P-(O-GalNAc)T-TDSTTPAPTTK Mus musculus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + GTTPSPVPTTSTTSAP 0.3% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + GTTPSPVPTTSTTSAP 73% of the activity with P-(O-GalNAc)T-TDSTTPAPTTK Mus musculus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + P-(O-GalNAc)T-TDSTTPAPTTK
-
Mus musculus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + P-(O-GalNAc)T-TDSTTPAPTTK 0.3% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + PTTDS-(O-GalNAc)T-TPAPTTK 38.7% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Rattus norvegicus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + PTTDS-(O-GalNAc)T-TPAPTTK 4.5% of the activity with P-(O-GalNAc)T-TDSTTPAPTTK Mus musculus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + PTTDS-(O-GalNAc)T-TPAPTTK 59.6% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + PTTDSTTPAPTTK 0.3% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + PTTDSTTPAPTTK 74% of the activity with P-(O-GalNAc)T-TDSTTPAPTTK Mus musculus UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + VESDRSTTTTQAP 0.3% of the activity with GTTPSPVPTTS-(O-GalNAc)T-TSAP Toxoplasma gondii UDP + ?
-
?
UDP-N-acetyl-D-galactosamine + VESDRSTTTTQAP 34% of the activity with P-(O-GalNAc)T-TDSTTPAPTTK Mus musculus UDP + ?
-
?

Synonyms

Synonyms Comment Organism
ppGalNAc-T1
-
Mus musculus
ppGalNAc-T10
-
Rattus norvegicus
ppGalNAc-T3
-
Toxoplasma gondii
UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T1
-
Mus musculus
UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T10
-
Rattus norvegicus
UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T3
-
Toxoplasma gondii