Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | intraperitoneal administration of lipopolysaccharide, a potent inducer of systemic inflammation, strongly induces beta-1,4-GalT-I mRNA expression in the lung, heart, liver, spleen, kidney, lymph node, hippocampus, and testis, as well as in the cerebral cortex. In the rat lung, liver and testis, LPS stimulation of beta-1,4-GalT-I mRNA expression is time-dependent and biphasic | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | beta-1,4-GalT-I plays a key role in the synthesis of selectin ligands such as sialy Lewis, sLex, and sulfated sLex, overview. beta-1,4-GalT-I may play an important role in the inflammation reaction | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | - |
Rattus norvegicus | - |
endothelial cell | high expression level | Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
hippocampus | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
lymph node | - |
Rattus norvegicus | - |
macrophage | high expression level | Rattus norvegicus | - |
neutrophil | high expression level | Rattus norvegicus | - |
spleen | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | beta-1,4-GalT-I plays a key role in the synthesis of selectin ligands such as sialy Lewis, sLex, and sulfated sLex, overview. beta-1,4-GalT-I may play an important role in the inflammation reaction | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-1,4-galactosyltransferase-I | - |
Rattus norvegicus |
beta-1,4-GalT-I | - |
Rattus norvegicus |