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Literature summary for 2.4.1.38 extracted from

  • Qian, J.; Cheng, C.; Liu, H.; Chen, J.; Yan, M.; Niu, S.; Qin, J.; Sun, L.; Liu, L.; Gu, J.; Shen, A.
    Expression of beta-1,4-galactosyltransferase-I in rat during inflammation (2007), Inflammation, 30, 59-68.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information intraperitoneal administration of lipopolysaccharide, a potent inducer of systemic inflammation, strongly induces beta-1,4-GalT-I mRNA expression in the lung, heart, liver, spleen, kidney, lymph node, hippocampus, and testis, as well as in the cerebral cortex. In the rat lung, liver and testis, LPS stimulation of beta-1,4-GalT-I mRNA expression is time-dependent and biphasic Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus beta-1,4-GalT-I plays a key role in the synthesis of selectin ligands such as sialy Lewis, sLex, and sulfated sLex, overview. beta-1,4-GalT-I may play an important role in the inflammation reaction ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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male sprague-dawley rats
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Source Tissue

Source Tissue Comment Organism Textmining
cerebral cortex
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Rattus norvegicus
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endothelial cell high expression level Rattus norvegicus
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heart
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Rattus norvegicus
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hippocampus
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Rattus norvegicus
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kidney
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Rattus norvegicus
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liver
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Rattus norvegicus
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lung
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Rattus norvegicus
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lymph node
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Rattus norvegicus
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macrophage high expression level Rattus norvegicus
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neutrophil high expression level Rattus norvegicus
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spleen
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Rattus norvegicus
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testis
-
Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information beta-1,4-GalT-I plays a key role in the synthesis of selectin ligands such as sialy Lewis, sLex, and sulfated sLex, overview. beta-1,4-GalT-I may play an important role in the inflammation reaction Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
beta-1,4-galactosyltransferase-I
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Rattus norvegicus
beta-1,4-GalT-I
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Rattus norvegicus