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Literature summary for 2.4.1.17 extracted from
- UDP-glucuronosyltransferase isoforms catalyzing glucuronidation of hydroxy-polychlorinated biphenyls in rat (2005), Drug Metab. Dispos., 33, 1466-1476.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in yeast strain AH22 | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
| Rattus norvegicus | P08430 | - |
- |
| Rattus norvegicus | P08542 | - |
- |
| Rattus norvegicus | P09875 | - |
- |
| Rattus norvegicus | P36511 | - |
- |
| Rattus norvegicus | Q64550 | - |
- |
| Rattus norvegicus | Q64633 | - |
- |
| Rattus norvegicus | Q64637 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| hepatocyte | - |
Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| large intestine | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| lung | - |
Rattus norvegicus | - |
| small intestine | - |
Rattus norvegicus | - |
| testis | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-hydroxy-2',3',4',5'-tetrachlorobiphenyl + UDPglucuronate | - |
Rattus norvegicus | UDP + 2',3',4',5'-tetrachlorobiphenyl 2-O-glucuronate | - |
? |  |
| 4-hydroxy-2',3,3',4',5'-pentachlorobiphenyl + UDPglucuronate | - |
Rattus norvegicus | UDP + 2,3,3',4',5'-pentachlorobiphenyl 4-O-glucuronate | - |
? | |
| 4-hydroxy-2',3,3',4',5,5'-heptachlorobiphenyl + UDPglucuronate | - |
Rattus norvegicus | UDP + 2',3,3',4',5,5'-hexachlorobiphenyl 4-O-glucuronate | - |
? | |
| 4-hydroxy-2',3,4',5,6'-pentachlorobiphenyl + UDPglucuronate | - |
Rattus norvegicus | UDP + 2',3,4',5,6'-pentachlorobiphenyl 4-O-glucuronate | - |
? | |
| 4-hydroxy-2',3,4',6'-tetrachlorobiphenyl + UDP-glucuronate | - |
Rattus norvegicus | UDP + 2',4',6'-trichlorobiphenyl 4-O-glucuronate | - |
? | |
| 4-hydroxy-2',4',6'-trichlorobiphenyl + UDP-glucuronate | - |
Rattus norvegicus | UDP + 2',4',6'-trichlorobiphenyl 4-O-glucuronate | - |
? | |
| 4-methylumbeliferone + UDP-glucuronate | - |
Rattus norvegicus | 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
| testosterone + UDP-glucuronate | - |
Rattus norvegicus | UDP + testosterone beta-D-glucuronoside | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| UGT1A1 | - |
Rattus norvegicus |
| UGT1A3 | - |
Rattus norvegicus |
| UGT1A5 | - |
Rattus norvegicus |
| UGT1A6 | - |
Rattus norvegicus |
| UGT1A7 | - |
Rattus norvegicus |
| UGT2B1 | - |
Rattus norvegicus |
| UGT2B12 | - |
Rattus norvegicus |
| UGT2B3 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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