Cloned (Comment) | Organism |
---|---|
UGT1A1 expressed in HK-293 cells | Platyrrhini |
UGT1A1 expressed in HK293 cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5 | - |
2-hydroxyestradiol | - |
Platyrrhini | |
6 | - |
2-hydroxyestrone | - |
Platyrrhini | |
13 | - |
estradiol | - |
Platyrrhini |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Platyrrhini | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
UGT1 proteins by Western Blot | Homo sapiens |
55000 | - |
UGT1 proteins by Western Blot | Platyrrhini |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Platyrrhini | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-hydroxyestradiol + UDP-glucuronate | - |
Platyrrhini | UDP + 2-hydroxyestradiol O-glucuronide | - |
? | |
2-hydroxyestrone + UDPglucuronate | - |
Homo sapiens | 2-hydroxyestrone 2-O-glucuronide + UDP | - |
? | |
2-hydroxyestrone + UDPglucuronate | - |
Platyrrhini | 2-hydroxyestrone 2-O-glucuronide + UDP | - |
? | |
estradiol + UDPglucuronate | - |
Platyrrhini | UDP + estradiol O-glucuronide | - |
? |