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Literature summary for 2.4.1.17 extracted from

  • Matern, S.; Matern, H.; Farthmann, E.H.; Gerok, W.
    Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes (1984), J. Clin. Invest., 74, 402-410.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chenodeoxycholic acid + UDP-glucuronate low activity in patients with liver cirrhosis and granulomatous hepatitis Homo sapiens UDP + ?
-
 ?
deoxycholic acid + UDPglucuronate
-
 Homo sapiens UDP + deoxycholic acid O-glucuronide
-
 ?
glycolithocholic acid + UDPglucuronate lowest activity among five bile acids studied Homo sapiens UDP + glycolithocholic acid O-glucuronide
-
 ?
lithocholic acid + UDPglucuronate highest activity among five bile acids studied Homo sapiens UDP + ?
-
 ?
ursodeoxycholic acid + UDPglucuronate highest activity among five bile acids studied Homo sapiens UDP + ursodeoxycholic acid O-glucuronide
-
 ?