Inhibitors | Comment | Organism | Structure |
---|---|---|---|
codeine | competitive inhibitor to morphine-UDPGT | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
56000 | - |
morphine-UDPGT, monomer | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
Wistar strain | - |
Rattus norvegicus Wistar | - |
Wistar strain | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxybiphenyl + UDP-glucuronate | no activity | Rattus norvegicus | UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide | - |
? | |
4-hydroxybiphenyl + UDP-glucuronate | no activity | Rattus norvegicus Wistar | UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide | - |
? | |
alpha-naphthylamine + UDPglucuronate | inactive | Rattus norvegicus | UDP + ? | - |
? | |
bilirubin + UDPglucuronate | no activity | Rattus norvegicus | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
bilirubin + UDPglucuronate | no activity | Rattus norvegicus Wistar | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
estrone + UDPglucuronate | inactive | Homo sapiens | UDP + estrone 3-O-glucuronide | - |
? | |
additional information | no activity with androsterone | Rattus norvegicus | ? | - |
? | |
additional information | 36 substrates for HGT2B7H and HGT2B7Y. HGT2B7 glucuronidates both hydroxyl and carboxyl functions of bile acids, retinols and hydroxylated fatty acids | Homo sapiens | ? | - |
? | |
additional information | no activity with androsterone | Rattus norvegicus Wistar | ? | - |
? | |
morphine + UDP-glucuronate | - |
Homo sapiens | UDP + morphine 3,6-diglucuronide | - |
? | |
morphine + UDP-glucuronate | - |
Rattus norvegicus | UDP + morphine 3,6-diglucuronide | - |
? | |
morphine + UDP-glucuronate | - |
Rattus norvegicus Wistar | UDP + morphine 3,6-diglucuronide | - |
? | |
testosterone + UDPglucuronate | no activity | Homo sapiens | UDP + testosterone O-glucuronide | - |
? | |
testosterone + UDPglucuronate | no activity | Rattus norvegicus | UDP + testosterone O-glucuronide | - |
? | |
testosterone + UDPglucuronate | no activity | Rattus norvegicus Wistar | UDP + testosterone O-glucuronide | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | by chromatofocusing | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1.1 | - |
codeine | competitive with morphine glucuronidation | Rattus norvegicus |