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Literature summary for 2.4.1.17 extracted from
- Purification and properties of a rat liver phenobarbital-inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase (1991), Mol. Pharmacol., 40, 80-84.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.26 | - |
4-Hydroxybiphenyl | - |
Rattus norvegicus |  |
| 1 | - |
UDPglucuronate | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 52500 | - |
x * 52500 | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | N-glycosylated | Rattus norvegicus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-hydroxybiphenyl + UDP-glucuronate | - |
Rattus norvegicus | UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide | - |
? | |
| 4-hydroxybiphenyl + UDPglucuronate | - |
Rattus norvegicus | UDP + 4-hydroxybiphenyl 4-O-beta-D-glucuronide | - |
? | |
| 4-methylumbelliferone + UDP-glucuronate | - |
Rattus norvegicus | UDP + 4-methylumbelliferyl-7-O-beta-D-glucuronide | - |
? | |
| 4-nitrophenol + UDP-glucuronate | - |
Rattus norvegicus | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
| additional information | no activity with androsterone | Rattus norvegicus | ? | - |
? | |
| additional information | no activity with 4-hydroxycoumarin or 7-methoxycoumarin, conjugation of androsterone | Rattus norvegicus | ? | - |
? | |
| testosterone + UDPglucuronate | no activity | Rattus norvegicus | UDP + testosterone O-glucuronide | - |
? | |
| UDP-alpha-D-glucuronate + chloramphenicol | no activity | Rattus norvegicus | UDP + chloramphenicol beta-D-glucuronide | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 52500 | Rattus norvegicus |
| ? | all values determined by SDS-PAGE | Rattus norvegicus |
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