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Literature summary for 2.4.1.17 extracted from

  • Fournel-Gigleux, S.; Shepherd, S.R.P.; Carre, M.C.; Burchell, B.; Siest, G.; Caubere, P.
    Novel inhibitors and substrates of bilirubin: UDP-glucuronosyltransferase. Arylalkylcarboxylic acids (1989), Eur. J. Biochem., 183, 653-659.
    View publication on PubMed
Search for more literature for 2.4.1.17

Inhibitors

Inhibitors Comment Organism Structure
3,3,3-Triphenylpropionic acid competitive to bilirubin Rattus norvegicus
4,4,4-Triphenylbutanoic acid competitive to bilirubin Rattus norvegicus
5,5,5-Triphenylpentanoic acid competitive to bilirubin Rattus norvegicus
6,6,6-Triphenylhexanoic acid competitive to bilirubin Rattus norvegicus
7,7,7-Triphenylheptanoic acid competitive to bilirubin Rattus norvegicus
8,8,8-Triphenyloctanoic acid competitive to bilirubin Rattus norvegicus
9,9,9-Triphenylnonanoic acid non-competitive to bilirubin Rattus norvegicus
Triphenylacetic acid competitive to bilirubin Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Wistar strain
-
Rattus norvegicus
-
 Gunn strain
-
Rattus norvegicus Gunn
-
 Gunn strain
-
Rattus norvegicus Wistar
-
 Wistar strain
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bilirubin + UDPglucuronate
-
 Rattus norvegicus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate
-
 Rattus norvegicus Gunn bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate
-
 Rattus norvegicus Wistar bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?